The following oral presentations have been confirmed at the 2017 Conference on HHV-6 & 7.

Keynote
Setting Boundaries: How cells keep Telomeres in check Eros Denchi Scripps Research Institute
Latent human cytomegalovirus infection – changes in the latently infected cell which optimise latent carriage and reactivation John Sinclair University of Cambridge
Inherited ciHHV-6
State of the art: Human herpesvirus 6A/B and chromosomal integration. Louis Flamand Laval University
CHU de Quebec Research Center
Exploring variation in epigenetic modification of inherited ciHHV-6 genomes and relationship with telomere length Nicola Royle University of Leicester
Prevalence of inherited chromosomally integrated HHV-6 and frequency of common ancestral integrations within the UK Ruth Jarrett University of Glasgow
Uncovering factors involved in human herpes 6 (HHV-6) integration into host telomeres Darren Wight Freie Universität Berlin
A rash of human herpesvirus 6 genomes reveals recombination and limited diversity of ciHHV-6 strains Alex Greninger University of Washington Medicine
Herpesvirus integration: from primates to fish, ancient and extant Amr Aswad St. Hilda’s College, University of Oxford
Host-Cell Interaction
HHV-6 infection and the cellular receptor Yasuko Mori Kobe University Graduate School of Medicine
Mechanisms of infection by HHV-6A/B Per Höllsberg Aarhus University
Induction of CCR2, CXCR3 and CX3CR1 receptors/ligands at the NK/endometrium interface during HHV-6A infection: a possible mechanism of interference with NK cell recruitment during embryo implantation Roberta Rizzo University of Ferrara
Role of the ND10 complex in the decision between lytic replication and latency of human herpesvirus-6 Anirban Sanyal Freie Universitӓt Berlin
Coexpression of HHV-6B gH/gL/gQ1/gQ2 complex with gB induces cell-cell fusion in CD134 expression cells, and gQ1 and gQ2 are key players for their mediated-cell fusion Aika Wakata Kobe University Graduate School of Medicine
HHV-6A/6B infection of NK cells modulates the expression of miRNAs and transcriptional factors potentially associated to impaired NK activity Elisabetta Caselli University of Ferrara
Visualization of the herpesvirus genomes in living cells Tereza Faflikova Freie Universität Berlin
Alterations in the PKR-eIF2α stress pathway and evidence for restricted propagation of human herpesvirus 6A (HHV-6A), utilizing variable input m.o.i.s. Eyal Sharon Tel Aviv University
HHV-6 Genes & Proteins
Role for the promyelocytic leukemia protein in human herpesvirus 6A/B chromosomal integration Vanessa Collin CHU de Quebec Research Center
Structure-based analysis of human herpesvirus 6A immediate early protein 2 Mitsuhiro Nishimura Kobe University Graduate School of Medicine
Interactions between U24 from HHV-6 and 7 and WW domains Suzana K. Straus University of British Columbia
Chromatin landscape of the latent ciHHV-6 genome Anthony Saviola University of Vermont
Innate & Acquired Immunity
Defining viral epitopes that drive the CD4 T cell response to HHV-6B Lawrence J. Stern University of Massachusetts Medical School
CD8 T cell responses to human herpesvirus 6B Andreas Moosmann Helmholtz-Zentrum München
STING-STAT6 signaling control NK cell activation and cytokine production during HHV-6A, HHV-6B and HHV-7 infection Daria Bortolotti University of Ferrara
The gH/gL/gQ1/gQ2 complex could induce protective immunity for HHV-6B Akiko Kawabata Kobe University Graduate School of Medicine
GVHD & DIHS/DRESS
HHV-6B and acute graft-versus-host-disease (aGVHD): true cause and effect? Danielle Zerr University of Washington &
Seattle Children’s Hospital
A new approach to studying the genome-wide CD4 T cell response to HHV-6B Derek Hanson Fred Hutchinson Cancer Research Center
The complex interaction between drug allergy and viral reactivation Tetsuo Shiohara Kyorin University School of Medicine
Drug hypersensitivity and HHV-6 infection: a review of viral involvement in organ dysfunction Vincent Descamps University Paris Diderot;
Bichat Claude Bernard Hospital; INSERM Unit 976 Saint Louis Hospital
Transplantation
State-of-the-Art in Transplantation: Closing the Gap Between HHV-6 Association and Causation Joshua A. Hill Fred Hutchinson Cancer Research Center and University of Washington
HHV-6 Infection in Pediatric Transplant Patients Tetsushi Yoshikawa Fujita Health University School of Medicine
Human Herpesvirus 6B (HHV-6B) Selectively Depletes CD4+ Cells In Vitro and In Vivo: Does Early Reactivation Impair CD4+ Reconstitution After HSCT, Thus Increasing the Risk of Grade 2-4 aGVHD? David M. Koelle University of Washington
HHV-6 and associated outcomes in context of immune reconstitution after pediatric hematopoietic cell transplantation Coco de Koning University Medical Center Utrecht
HHV6 specific T-cells to predict HHV-6 infection after allogeneic HSCT Raffaella Greco San Raffaele Scientific Institute
Clinical characteristics and outcome of HHV-6 encephalitis after allogeneic hematopoietic stem cell transplantation: results from a Japanese nationwide study Masao Ogata Oita University Faculty of Medicine
Human herpes virus 6 related acute encephalitis as a major diagnostic and therapeutic challenge after haploidentical stem cell transplantation Daniele Mannina San Raffaele Hospital
Human herpesvirus 6 in lower respiratory tract disease after allogeneic hematopoietic cell transplantation: pathogen or bystander? Joshua A. Hill Fred Hutchinson Cancer Research Center and University of Washington
Clinical and histopathologic manifestations of Human Herpersvirus-6 (HHV6) infection in pediatric liver transplant recipients at Texas Children’s Hospital Krupa R. Mysore Texas Children’s hospital
Baylor College of Medicine
Treatment
Foscarnet for the prevention of HHV-6 encephalitis in cord blood transplant recipients: A multicenter, open-label, single-arm, phase 2 trial Takahiro Fukuda National Cancer Center Hospital
Adoptive immunotherapy for viral infections Ifigeneia Tzannou Baylor College of Medicine
Drug development for beta-herpesviruses Ravit Boger John Hopkins University School of Medicine
Path to Treatment
Facilitating drug development for the prevention of HHV-6 disease in transplantation settings: lessons from collaborative approaches Veronica Miller Forum for Collaborative Research;
UC Berkeley SPH
Defining HHV-6 Disease Michael Boeckh The Fred Hutchinson Cancer Research Center
University of Washington
Non-CNS Disease
HHV-6 glycoprotein B is present in human pancreatic islets from patients with type 1 diabetes, but not auto-antibody positive donors or donors without diabetes Matthias von Herrath La Jolla Institute
Clinical features of primary human herpesvirus 6B infection in a cohort of acute care visits Fumihiko Hattori Fujita Health University School of Medicine
Human herpesvirus 6 (HHV-6) in patients presenting with heart muscle diseases: an update Dirk Lassner Institute for Cardiac Diagnosis & Treatment
Evidence of human herpesvirus-6 and -7 reactivation in miscarrying women with pityriasis rosea. Francesco Drago University of Genoa
HHV-6 in salivary glands and salivary gland tumors S. David Hudnall Yale University School of Medicine
CNS Disease
Serological response against an immediate-early 1 protein sequence from HHV-6A is positively associated with risk for multiple sclerosis Anna Fogdell-Hahn Karolinska Institutet
Center for Molecular Medicine
Detection of chromosomally integrated HHV-6 DNA and RNA expression in PBMC and brain tissues Cheng-Te Major Lin NIH, NINDS
Infection of cerebellum with HHV-6A is increased in mood disorders and associated with gene set enrichment of viral and toll-like receptor pathways Bhupesh Prusty University of Würzburg
Diagnostics
What’s new in HHV-6 diagnostics? Keith Jerome University of Washington
Fred Hutchinson Cancer Research Center
Towards ensuring the quality of HHV-6 diagnosis in immunocompromised patients Sheila Govind National Institute for Biological Standards and Control (NIBSC)
IciHHV-6: Estimation of the number of HHV-6 genomic copies integrated using quantitative real-time PCR and droplet digital PCR assays Agnes Gautheret-Dejean Groupe Hospitalier Pitie-Salpetriere
Animal Models
Persistent HHV-6A brain infection in CD46-transgenic mice associated to behavioral disorder Branka Horvat National Institute Of Health and Medical Research (INSERM)
Role of innate DNA receptors in HHV-6A infection Cynthia Leifer Cornell University
HHV-6 EAE marmoset model Steve Jacobson National Institute of Neurological Disorders and Stroke
Murine roseolovirus (MRV): pathogenesis and immunity Swapneel Patel Washington University School of Medicine